Interferon gamma 抗体
Quick Overview for Interferon gamma 抗体 (ABIN966336)
抗原
See all Interferon gamma (IFNG) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)
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纯化方法
- Antibodies are purified by protein A affinity chromatography
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亚型
- IgG1
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应用备注
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Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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储存条件
- -20 °C
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Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, (1999) (PubMed).
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Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, (1999) (PubMed).
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- Interferon gamma (IFNG)
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别名
- IFN-Y
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背景
- Interferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
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基因ID
- 3458
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途径
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
抗原
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