MLL/KMT2A 抗体 (N-Term)
(7 references)Our Local Distributor
北京 101111
Quick Overview for MLL/KMT2A 抗体 (N-Term) (ABIN966301)
抗原
See all MLL/KMT2A (MLL) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near N-terminal residues of human HRX (Histone-lysine N-methyltransferase HRX)
-
-
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibody
MLL 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3751-3968) antibodyMLL 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 10F8D7 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 801-956) antibodyMLL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4A5A12 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 2829-2883) antibodyMLL 适用: 人, 小鼠 WB, ChIP, ICC, ChIP-seq, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3561-3670) antibodyMLL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3879-3908), (C-Term) antibodyMLL 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal RB02951 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (C-Term) antibodyMLL 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C
-
-
-
: "Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias." in: British journal of haematology, Vol. 93, Issue 4, pp. 966-72, (1996) (PubMed).
: "The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing." in: DNA and cell biology, Vol. 14, Issue 6, pp. 475-83, (1995) (PubMed).
: "Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia." in: Cancer research, Vol. 54, Issue 9, pp. 2327-30, (1994) (PubMed).
: "Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia." in: Oncogene, Vol. 8, Issue 10, pp. 2617-25, (1993) (PubMed).
: "Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias." in: Cell, Vol. 71, Issue 4, pp. 691-700, (1992) (PubMed).
: "The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene." in: Cell, Vol. 71, Issue 4, pp. 701-8, (1992) (PubMed).
: "Cloning a replication function from the streptomycete bacteriophage FP43." in: Gene, Vol. 113, Issue 1, pp. 113-7, (1992) (PubMed).
-
: "Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias." in: British journal of haematology, Vol. 93, Issue 4, pp. 966-72, (1996) (PubMed).
-
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
-
别名
- HRX
-
背景
-
HRX (Histone-lysine N-methyltransferase HRX) functions as histone methyltransferase. HRX methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. HRX promotes PPP1R15A-induced apoptosis. HRX interacts with SBF1 and PPP1R15A. HRX is a component of the MLL complex, at least composed of MLL, ASH2L, RBBP5, DPY30, WDR5, MEN1,HCFC1 and HCFC2. Chromosomal aberrations involving MLL are a cause of acute leukemias. A chromosomal aberration involving MLL may be a cause of chronic neutrophilic leukemia. HRX belongs to the histone-lysine methyltransferase family and TRX/MLL subfamily.
Synonyms: ALL1, CXXC7(CXXC-type zinc finger protein 7), HTRX, KMT2A, TRX1, MLL, Zinc finger protein HRX, Trithorax-like protein, Lysine N-methyltransferase 2A -
途径
- Warburg Effect
抗原
-
