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GSTP1 抗体

GSTP1 适用: 人 WB, ELISA, IHC Monoclonal unconjugated
产品编号 ABIN966240
发货至: 中国
  • 抗原 See all GSTP1 抗体
    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
    适用
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    克隆类型
    • 88
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    单克隆
    标记
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    This GSTP1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3)
    纯化方法
    Antibodies are purified by protein A affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product GSTP1 Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    IHC(F): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 储存条件
    -20 °C
  • Lin, Nelson: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." in: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).

    Satoh, Itoh, Yamamoto, Tanaka, Hayakari, Ookawa, Yamazaki, Sato, Tsuchida, Hatayama: "Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells." in: Carcinogenesis, Vol. 23, Issue 3, pp. 457-62, (2002) (PubMed).

  • 抗原
    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
    别名
    GSTP1 (GSTP1 产品)
    别名
    DFN7 antibody, FAEES3 antibody, GST3 antibody, GSTP antibody, PI antibody, GST-P antibody, Gst3 antibody, Gstp antibody, Gstp2 antibody, gst-Pi antibody, GstpiB antibody, glutathione S-transferase P-like antibody, glutathione S-transferase pi 1 antibody, glutathione S-transferase pi 1 L homeolog antibody, glutathione S-transferase, pi 1 antibody, LOC100739163 antibody, GSTP1 antibody, Gstp1 antibody, LOC100861197 antibody, gstp1.L antibody
    背景
    GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
    基因ID
    2950
    途径
    Cellular Response to Molecule of Bacterial Origin
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