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GSTP1 抗体

GSTP1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3F2C2 unconjugated
产品编号 ABIN1724656
发货至: 中国
  • 抗原 See all GSTP1 抗体
    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 88
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    单克隆
    标记
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    This GSTP1 antibody is un-conjugated
    应用范围
    • 103
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human GSTP1 expressed in E. coli.
    克隆位点
    3F2C2
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Lin, Nelson: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." in: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).

    Satoh, Itoh, Yamamoto, Tanaka, Hayakari, Ookawa, Yamazaki, Sato, Tsuchida, Hatayama: "Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells." in: Carcinogenesis, Vol. 23, Issue 3, pp. 457-62, (2002) (PubMed).

  • 抗原
    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
    别名
    GSTP1 (GSTP1 产品)
    别名
    DFN7 antibody, FAEES3 antibody, GST3 antibody, GSTP antibody, PI antibody, GST-P antibody, Gst3 antibody, Gstp antibody, Gstp2 antibody, gst-Pi antibody, GstpiB antibody, glutathione S-transferase P-like antibody, glutathione S-transferase pi 1 antibody, glutathione S-transferase pi 1 L homeolog antibody, glutathione S-transferase, pi 1 antibody, LOC100739163 antibody, GSTP1 antibody, Gstp1 antibody, LOC100861197 antibody, gstp1.L antibody
    背景

    Description: GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90 % ) of prostate carcinomas and is associated with transcriptional down-regulation.

    Aliases: PI, DFN7, GST3, FAEES3

    分子量
    23 kDa
    基因ID
    2950
    HGNC
    2950
    途径
    Cellular Response to Molecule of Bacterial Origin
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