GSTP1 抗体
(2 references)Quick Overview for GSTP1 抗体 (ABIN966240)
抗原
See all GSTP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3)
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纯化方法
- Antibodies are purified by protein A affinity chromatography
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亚型
- IgG1
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anti-Glutathione S-Transferase pi 1 (GSTP1) antibody
GSTP1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3F2C2 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 2-210) antibodyGSTP1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1A7B5 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 97-126) antibodyGSTP1 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20807 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2G6-F6 unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 2-210) antibodyGSTP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) antibodyGSTP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase pi 1 (GSTP1) (N-Term) antibodyGSTP1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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储存条件
- -20 °C
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: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." in: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).
: "Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells." in: Carcinogenesis, Vol. 23, Issue 3, pp. 457-62, (2002) (PubMed).
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: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." in: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).
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- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
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别名
- GSTP1
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背景
- GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
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基因ID
- 2950
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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