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- 抗原 See all EHMT1 抗体
- EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))
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适用
- 人
- 宿主
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克隆类型
- 单克隆
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标记
- This EHMT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Ni-NTA purified truncated recombinant GLP expressed in E. Coli strain BL21 (DE3)
- 纯化方法
- Antibodies are purified by protein A affinity chromatography
- 亚型
- IgG1
- Top Product
- Discover our top product EHMT1 Primary Antibody
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- 应用备注
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Western Blot: Dilution 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 储存条件
- -20 °C
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Inhibition of glucagon secretion." in: Advances in pharmacology (San Diego, Calif.), Vol. 52, pp. 151-71, (2006) (PubMed).
: "Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus." in: The international journal of biochemistry & cell biology, Vol. 38, Issue 5-6, pp. 845-59, (2006) (PubMed).
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Inhibition of glucagon secretion." in: Advances in pharmacology (San Diego, Calif.), Vol. 52, pp. 151-71, (2006) (PubMed).
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- 抗原
- EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))
- 别名
- GLP (EHMT1 产品)
- 背景
- Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.
- 基因ID
- 79813
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