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GAPDH 抗体 (N-Term)

GAPDH 适用: 人 WB, IHC (p), ICC, IHC (f) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966181
发货至: 中国
  • 抗原 See all GAPDH 抗体
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    抗原表位
    • 37
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    N-Term
    适用
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    宿主
    • 159
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    克隆类型
    • 180
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    多克隆
    标记
    • 156
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    This GAPDH antibody is un-conjugated
    应用范围
    • 234
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminal of human GAPDH , identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.
    亚型
    IgG
    Top Product
    Discover our top product GAPDH Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Colell, Ricci, Tait, Milasta, Maurer, Bouchier-Hayes, Fitzgerald, Guio-Carrion, Waterhouse, Li, Mari, Barbry, Newmeyer, Beere, Green: "GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation." in: Cell, Vol. 129, Issue 5, pp. 983-97, (2007) (PubMed).

    Benham, Povey: "Members of the human glyceraldehyde-3-phosphate dehydrogenase-related gene family map to dispersed chromosomal locations." in: Genomics, Vol. 5, Issue 2, pp. 209-14, (1989) (PubMed).

  • 抗原
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    别名
    Glyceraldehyde-3-phosphate dehydrogenase(GAPDH) (GAPDH 产品)
    别名
    G3PD antibody, GAPD antibody, Gapd antibody, BEST:GH12586 antibody, CG12055 antibody, Dmel\\CG12055 antibody, GA3PDH antibody, GADPH antibody, GAP antibody, GAPDH antibody, GAPDH I antibody, GAPDH-1 antibody, GAPDH1 antibody, GAPDHI antibody, Gapdh antibody, Gapdh-1 antibody, Gapdh43E antibody, gadph antibody, gapdh antibody, gapdh-1 antibody, gh12586 antibody, cb609 antibody, gapd antibody, mg:bb02e05 antibody, wu:fb33a10 antibody, wu:ft80f05 antibody, KNC-NDS6 antibody, g3pd antibody, G3PDH antibody, glyceraldehyde-3-phosphate dehydrogenase antibody, Glyceraldehyde 3 phosphate dehydrogenase 1 antibody, glyceraldehyde-3-phosphate dehydrogenase S homeolog antibody, glyceraldehyde-3-phosphate dehydrogenase, type I antibody, olfactory receptor 8K3 antibody, GAPDH antibody, Gapdh antibody, Gapdh1 antibody, gapdh antibody, gapdh.S antibody, gapDH antibody, LOC100404960 antibody, LOC614985 antibody
    背景
    Glyceraldehyde-3-phosphate dehydrogenase catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme is thought to be a tetramer of identical chains. Several highly homologous glyceraldehyde-3-phosphate dehydrogenase (GAPD)-related sequences have been identified previously in human DNA by Southern blot analysis. Protein studies have identified only a single expressed locus for this major glycolytic enzyme, and this maps to chromosome 12p13. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a critical regulator of CICD, it mediates an elevation in glycolysis and enhanced autophagy that cooperate to protect cells from CICD.
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