Estrogen Receptor alpha 抗体 (AA 410-592)
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北京 101111
Quick Overview for Estrogen Receptor alpha 抗体 (AA 410-592) (ABIN966081)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 410-592
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纯化方法
- Purified
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免疫原
- Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli.
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亚型
- IgG1
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anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ESR1-1904 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibodyESR1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ESR1-3557 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6E8 unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer167) antibodyESR1 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (C-Term) antibodyESR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal ER506 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33807 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibodyESR1 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer118) antibodyESR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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缓冲液
- PBS
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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: "Estrogen receptor immunocytochemistry in paraffin embedded tissues with ER1D5 predicts breast cancer endocrine response more accurately than H222Sp gamma in frozen sections or cytosol-based ligand-binding assays." in: Cancer, Vol. 77, Issue 12, pp. 2514-9, (1996) (PubMed).
: "Estrogen receptor immunocytochemistry in endometrial carcinoma: a prognostic marker for survival." in: Gynecologic oncology, Vol. 63, Issue 1, pp. 28-33, (1996) (PubMed).
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: "Estrogen receptor immunocytochemistry in paraffin embedded tissues with ER1D5 predicts breast cancer endocrine response more accurately than H222Sp gamma in frozen sections or cytosol-based ligand-binding assays." in: Cancer, Vol. 77, Issue 12, pp. 2514-9, (1996) (PubMed).
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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别名
- ER-alpha
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背景
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The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells.
Synonyms: ER, ESR1, Era, ESRA -
基因ID
- 2099
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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