(4 references)-
- 抗原 See all ELK1 抗体
- ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
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适用
- 人
- 宿主
- 请咨询
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克隆类型
- 单克隆
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标记
- This ELK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- Ni-NTA purified truncated recombinant ELK1 expressed in E. Coli strain BL21 (DE3).
- 纯化方法
- Ascites.
- 亚型
- IgG1
- Top Product
- Discover our top product ELK1 Primary Antibody
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anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer383) antibody
ELK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer389) antibodyELK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (C-Term) antibodyELK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) antibodyELK1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3H6D12 unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer383) antibodyELK1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (AA 247-403) antibodyELK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pThr417) antibodyELK1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer389) antibodyELK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer383) antibodyELK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (AA 67-166) antibodyELK1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 2G6 unconjugated
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- 应用备注
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Western Blot: 1: 500- 1: 1,000
IHC(P): 1: 500- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存条件
- -20 °C
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: "PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells." in: Biochemical and biophysical research communications, Vol. 339, Issue 1, pp. 217-25, (2005) (PubMed).
: "Activation of ternary complex factor Elk-1 by stress-activated protein kinases." in: Current biology : CB, Vol. 5, Issue 10, pp. 1191-200, (1996) (PubMed).
: "ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation." in: The EMBO journal, Vol. 14, Issue 5, pp. 951-62, (1995) (PubMed).
: "elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints." in: Science (New York, N.Y.), Vol. 244, Issue 4900, pp. 66-70, (1989) (PubMed).
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: "PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells." in: Biochemical and biophysical research communications, Vol. 339, Issue 1, pp. 217-25, (2005) (PubMed).
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- 抗原
- ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
- 别名
- ELK1 (ELK1 产品)
- 别名
- Elk-1 antibody, Xelk antibody, Xelk-1 antibody, elk-1 antibody, elk1 antibody, ELK1, ETS transcription factor antibody, ELK1, member of ETS oncogene family antibody, ETS domain-containing protein Elk-1 antibody, ELK1, member of ETS oncogene family S homeolog antibody, ELK1 antibody, Elk1 antibody, Tsp_02690 antibody, elk1 antibody, elk1.S antibody
- 背景
- The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.
- 基因ID
- 2002
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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