DNAJA3 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for DNAJA3 抗体 (C-Term) (ABIN966005)
抗原
See all DNAJA3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Purified by antigen-specific affinity chromatography.
-
免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse DnaJa3 (DnaJ homolog subfamily A member 3, mitochondrial precursor)
-
-
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 86-184) antibody
DNAJA3 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 221-480) antibodyDNAJA3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 1-480) antibodyDNAJA3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 1-446) antibodyDNAJA3 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (Center) antibodyDNAJA3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (C-Term) antibodyDNAJA3 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) antibodyDNAJA3 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- This antibody is stored in PBS, 50% glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))
-
别名
- DnaJa3
-
背景
- DnaJa3(DnaJ homolog subfamily A member 3) modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. DnaJa3 affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C, in sharp contrast, isoform 2 suppresses apoptosis. DnaJa3 can modulate IFN-gamma-mediated transcriptional activity. It interacts with JAK2, HSPA9B and IFN-gammaR2 chain. It also interacts with Ras GTPase-activating protein 1 (RASA1). Modulation of apoptosis, i.e proapoptotic activity of isoform 1 and antiapoptotic activity of isoform 2, is J domaindependent. DnaJa3 contains 1 CR domain and 1 J domain.
-
途径
- Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity
抗原
-
