DNAJA3 抗体 (C-Term)
Quick Overview for DNAJA3 抗体 (C-Term) (ABIN966005)
抗原
See all DNAJA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse DnaJa3 (DnaJ homolog subfamily A member 3, mitochondrial precursor)
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anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 86-184) antibody
DNAJA3 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 1-480) antibodyDNAJA3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 1-446) antibodyDNAJA3 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (AA 221-480) antibodyDNAJA3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) (Center) antibodyDNAJA3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3) antibodyDNAJA3 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))
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别名
- DnaJa3
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背景
- DnaJa3(DnaJ homolog subfamily A member 3) modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. DnaJa3 affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C, in sharp contrast, isoform 2 suppresses apoptosis. DnaJa3 can modulate IFN-gamma-mediated transcriptional activity. It interacts with JAK2, HSPA9B and IFN-gammaR2 chain. It also interacts with Ras GTPase-activating protein 1 (RASA1). Modulation of apoptosis, i.e proapoptotic activity of isoform 1 and antiapoptotic activity of isoform 2, is J domaindependent. DnaJa3 contains 1 CR domain and 1 J domain.
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途径
- Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity
抗原
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