Desmin 抗体
Quick Overview for Desmin 抗体 (ABIN965993)
抗原
See all Desmin (DES) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified truncated recombinant Desmin expressed in E. Coli strain BL21 (DE3)
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亚型
- IgG1
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应用备注
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Western Blot: 1: 1,000- 1: 2,000
IHC(P): 1: 1,000- 1: 2,000
IHC(F): 1: 1,000- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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储存条件
- -20 °C
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Desmin modulates lung elastic recoil and airway responsiveness." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 5, pp. L890-6, (2006) (PubMed).
: "Protein kinase C-mediated desmin phosphorylation is related to myofibril disarray in cardiomyopathic hamster heart." in: Experimental biology and medicine (Maywood, N.J.), Vol. 227, Issue 11, pp. 1039-46, (2002) (PubMed).
: "
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Desmin modulates lung elastic recoil and airway responsiveness." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 5, pp. L890-6, (2006) (PubMed).
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- Desmin (DES)
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别名
- Desmin
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背景
- Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
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基因ID
- 1674
抗原
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