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Desmin 抗体

This anti-Desmin antibody is a 单克隆 antibody detecting Desmin in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN965993
发货至: 中国

Quick Overview for Desmin 抗体 (ABIN965993)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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宿主

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克隆类型

  • 115
  • 87
  • 1
单克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 特异性

    Ni-NTA purified truncated recombinant Desmin expressed in E. Coli strain BL21 (DE3)

    亚型

    IgG1
  • 应用备注

    Western Blot: 1: 1,000- 1: 2,000
    IHC(P): 1: 1,000- 1: 2,000
    IHC(F): 1: 1,000- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存条件

    -20 °C
  • Shardonofsky, Capetanaki, Boriek: "Desmin modulates lung elastic recoil and airway responsiveness." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 5, pp. L890-6, (2006) (PubMed).

    Huang, Li, Foster, Lemanski, Dube, Zhang, Lemanski: "Protein kinase C-mediated desmin phosphorylation is related to myofibril disarray in cardiomyopathic hamster heart." in: Experimental biology and medicine (Maywood, N.J.), Vol. 227, Issue 11, pp. 1039-46, (2002) (PubMed).

  • 抗原

    Desmin (DES)

    别名

    Desmin

    背景

    Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

    基因ID

    1674
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