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CrkL 抗体

CRKL 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5E12 unconjugated
产品编号 ABIN965932
发货至: 中国
  • 抗原 See all CrkL (CRKL) 抗体
    CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
    适用
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    宿主
    • 116
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CrkL antibody is un-conjugated
    应用范围
    • 77
    • 45
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CRKL expressed in E. Coli.
    克隆位点
    5E12
    亚型
    IgG1
    Top Product
    Discover our top product CRKL Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Seo, Suenaga, Hatakeyama, Taiji, Imamoto: "Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop." in: Molecular and cellular biology, Vol. 29, Issue 11, pp. 3076-87, (2009) (PubMed).

  • 抗原
    CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
    别名
    CRKL (CRKL 产品)
    别名
    CRKL antibody, wu:fa55g05 antibody, wu:fj60e01 antibody, zgc:63469 antibody, 1110025F07Rik antibody, AA589403 antibody, AI325100 antibody, Crkol antibody, CRK like proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog-like antibody, CRKL antibody, crkl antibody, Crkl antibody
    背景
    This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
    Synonyms: CRKL
    分子量
    39kDa
    基因ID
    1399
    途径
    Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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