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CDK9 抗体

This anti-CDK9 antibody is a 小鼠 单克隆 antibody detecting CDK9 in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN965846
发货至: 中国

Quick Overview for CDK9 抗体 (ABIN965846)

抗原

See all CDK9 抗体
CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

适用

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宿主

  • 96
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小鼠

克隆类型

  • 86
  • 16
单克隆

标记

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  • 3
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This CDK9 antibody is un-conjugated

应用范围

  • 77
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

1B5D10
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CDK9 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Montanuy, Torremocha, Hernández-Munain, Suñé: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).

    Sabò, Lusic, Cereseto, Giacca: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).

  • 抗原

    CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

    别名

    CDK9

    背景

    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
    Tissue specificity: Ubiquitous.
    Synonyms: TAK, C-2k, CTK1, CDC2L4, PITALRE

    分子量

    43kDa

    基因ID

    1025

    途径

    Cell Division Cycle
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