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CD80 抗体 (N-Term)

This anti-CD80 antibody is a 兔多克隆 antibody detecting CD80 in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

(2 references)

产品编号 ABIN965820

发货至: 中国

Quick Overview for CD80 抗体 (N-Term) (ABIN965820)

抗原

See all CD80 抗体

CD80

适用

182
96
45
6
6
6
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

This CD80 antibody is un-conjugated

应用范围

129
94
72
35
35
23
14
13
13
12
11
10
7
5
4
2
2
2
1
1
1
1
1

Western Blotting (WB)

Discover our top product CD80 Primary Antibody

抗原表位
34

16

15

12

8

7

6

4

4

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 57-71, N-Term

免疫原

A synthetic peptide corresponding to a sequence at the N-terminal of human CD80 (57-71aa), identical to the related mouse and rat sequence.
anti-CD80 (CD80) (AA 35-288) antibody
CD80 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 1G3D7 unconjugated

anti-CD80 (CD80) (AA 251-321) antibody
CD80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD80 (CD80) antibody
CD80 适用: 小鼠, 犬 FACS, IP, IHC (fro) 宿主: 仓鼠 Monoclonal 16-10A1 unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody
CD80 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-233 unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 FITC

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PE

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 APC

anti-CD80 (CD80) antibody
CD80 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2A2 unconjugated

anti-CD80 (CD80) (AA 111-265) antibody
CD80 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: The detection limit for CD80/ B7-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.

限制

仅限研究用
溶解方式

0.2ml of distilled water will yield a concentration of 500µg/ml.

缓冲液

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

储存液

Thimerosal (Merthiolate), Sodium azide

储存条件

-20 °C
Stamper, Zhang, Tobin, Erbe, Ikemizu, Davis, Stahl, Seehra, Somers, Mosyak: "Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses." in: Nature, Vol. 410, Issue 6828, pp. 608-11, (2001) (PubMed).

Peach, Bajorath, Naemura, Leytze, Greene, Aruffo, Linsley: "Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28." in: The Journal of biological chemistry, Vol. 270, Issue 36, pp. 21181-7, (1995) (PubMed).
抗原

CD80

别名

CD80

背景

Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al. (1997) stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints

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