CD4 抗体
Quick Overview for CD4 抗体 (ABIN965794)
抗原
See all CD4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified recombinant human CD4 expressed in E. Coli strain BL21 (DE3).
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纯化方法
- Antibodies are purified by protein A affinity chromatography
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亚型
- IgG1
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应用备注
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Western Blot, IHC and ELISA. Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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储存条件
- -20 °C
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: "Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).
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: "Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).
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- CD4
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别名
- CD4
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背景
- The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells
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基因ID
- 920
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途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
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