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CD20 抗体

This anti-CD20 antibody is a 小鼠 单克隆 antibody detecting CD20 in IHC, IF 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN965776
发货至: 中国

Quick Overview for CD20 抗体 (ABIN965776)

抗原

See all CD20 (MS4A1) 抗体
CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD20 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

克隆位点

3E9D3C1G3
  • 纯化方法

    Ascitic fluid

    免疫原

    Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Riley, Byar: "The rationale for and background of radioimmunotherapy: an emerging therapy for B-cell non-Hodgkin's lymphoma." in: Seminars in oncology nursing, Vol. 20, Issue 1 Suppl 1, pp. 1-7, (2004) (PubMed).

    Reiners, Hansen, Krüssmann, Schön, Csernok, Gross, Engert, Von Strandmann: "Selective killing of B-cell hybridomas targeting proteinase 3, Wegener's autoantigen." in: Immunology, Vol. 112, Issue 2, pp. 228-36, (2004) (PubMed).

    Byar: "Educating patients about radioimmunotherapy with yttrium 90 ibritumomab tiuxetan (Zevalin)." in: Seminars in oncology nursing, Vol. 20, Issue 1 Suppl 1, pp. 20-5, (2004) (PubMed).

  • 抗原

    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

    别名

    CD20

    背景

    CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
    Synonyms: B1, S7, Bp35, CD20, MS4A2, LEU-16, MGC3969, MS4A1

    基因ID

    931
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