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MME 抗体

This 单克隆 antibody specifically detects MME in IHC 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN965758
发货至: 中国
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Quick Overview for MME 抗体 (ABIN965758)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

适用

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克隆类型

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单克隆

标记

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This MME antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 特异性

    Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3).

    纯化方法

    Antibodies are purified by protein G affinity chromatography.

    亚型

    IgG2b
  • 应用备注

    IHC(P): Dilution 1: 100- 1: 200
    IHC(F): Dilution 1: 200- 1: 400
    ELISA: Propose dilution 1: 10000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存条件

    -20 °C
  • Sato, Itoh, Hinoda, Ohe, Nakagawa, Ueda, Yachi, Imai: "Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon." in: Journal of gastroenterology, Vol. 31, Issue 1, pp. 12-7, (1996) (PubMed).

    Inukai, Sugita, Iijima, Tezuka, Goi, Kojika, Shiraishi, Kagami, Nakazawa: "Expression of granulocyte colony-stimulating factor receptor on CD10-positive human B-cell precursors." in: British journal of haematology, Vol. 89, Issue 3, pp. 623-6, (1995) (PubMed).

  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    CD10

    物质类

    Chemical

    背景

    CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

    基因ID

    4311

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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