MME 抗体
Quick Overview for MME 抗体 (ABIN965758)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3).
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纯化方法
- Antibodies are purified by protein G affinity chromatography.
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亚型
- IgG2b
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应用备注
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IHC(P): Dilution 1: 100- 1: 200
IHC(F): Dilution 1: 200- 1: 400
ELISA: Propose dilution 1: 10000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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储存条件
- -20 °C
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: "Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon." in: Journal of gastroenterology, Vol. 31, Issue 1, pp. 12-7, (1996) (PubMed).
: "Expression of granulocyte colony-stimulating factor receptor on CD10-positive human B-cell precursors." in: British journal of haematology, Vol. 89, Issue 3, pp. 623-6, (1995) (PubMed).
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: "Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon." in: Journal of gastroenterology, Vol. 31, Issue 1, pp. 12-7, (1996) (PubMed).
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- CD10
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物质类
- Chemical
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背景
- CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
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基因ID
- 4311
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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