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c-FOS 抗体 (Middle Region)

This anti-c-FOS antibody is a 兔 多克隆 antibody detecting c-FOS in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN965712
发货至: 中国

Quick Overview for c-FOS 抗体 (Middle Region) (ABIN965712)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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宿主

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克隆类型

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多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    No cross reactivity with other proteins.

    产品特性

    Rabbit IgG polyclonal antibody for Proto-oncogene c-Fos (FOS) detection. Tested with WB in Human, Mouse, Rat.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human C-FOS, identical to the related rat and mouse sequences.< br/>Immunogen was affinity purified.

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Grigoriadis, Wang, Wagner: "Fos and bone cell development: lessons from a nuclear oncogene." in: Trends in genetics : TIG, Vol. 11, Issue 11, pp. 436-41, (1996) (PubMed).

    Saez, Rutberg, Mueller, Oppenheim, Smoluk, Yuspa, Spiegelman: "c-fos is required for malignant progression of skin tumors." in: Cell, Vol. 82, Issue 5, pp. 721-32, (1995) (PubMed).

    Barker, Rabin, Watson, Breg, Ruddle, Verma: "Human c-fos oncogene mapped within chromosomal region 14q21----q31." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, Issue 18, pp. 5826-30, (1984) (PubMed).

  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    Proto-oncogene c-Fos

    背景

    The human oncogene c-fos is cellular homolog of the transforming gene of Finkel-Biskis-Jinkins (FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. c-Fos is encoded by the FOS gene. FOS was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. FOS is also a major component of the activator protein-1 (AP-1) transcription factor complex, which includes members of the JUN family. c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al. (1995) established a unique role for the proto-oncogene and nuclear transcription factor, Fos, in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease.

    途径

    S100 Proteins
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