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Aurora Kinase B 抗体

This anti-Aurora Kinase B antibody is a 单克隆 antibody detecting Aurora Kinase B in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN965626
发货至: 中国

Quick Overview for Aurora Kinase B 抗体 (ABIN965626)

抗原

See all Aurora Kinase B (AURKB) 抗体
Aurora Kinase B (AURKB)

适用

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克隆类型

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单克隆

标记

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This Aurora Kinase B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    Ni-NTA purified truncated recombinant AURKB expressed in E. Coli strain BL21 (DE3)

    纯化方法

    Crude ascites.

    亚型

    IgG1
  • 应用备注

    Western Blot: 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C
  • Song, So, Cheng, Tang, Croft: "Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion." in: Immunity, Vol. 22, Issue 5, pp. 621-31, (2005) (PubMed).

    Kapoor, Lavoie, Frappier: "EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases." in: Molecular and cellular biology, Vol. 25, Issue 12, pp. 4934-45, (2005) (PubMed).

  • 抗原

    Aurora Kinase B (AURKB)

    别名

    AURKB

    背景

    AURKB (aurora kinase B, AIK2 or aurora-B), with 344amino acid protein(about 39kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis. It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases

    基因ID

    9212

    途径

    TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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