电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Androgen Receptor 抗体 (AA 689-919)

AR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9D12 unconjugated
产品编号 ABIN965588
发货至: 中国
  • 抗原 See all Androgen Receptor (AR) 抗体
    Androgen Receptor (AR)
    抗原表位
    • 21
    • 19
    • 19
    • 18
    • 17
    • 17
    • 15
    • 13
    • 13
    • 12
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 689-919
    适用
    • 299
    • 93
    • 88
    • 29
    • 19
    • 17
    • 15
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    宿主
    • 254
    • 48
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 246
    • 57
    单克隆
    标记
    • 112
    • 27
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Androgen Receptor antibody is un-conjugated
    应用范围
    • 180
    • 89
    • 65
    • 58
    • 53
    • 37
    • 29
    • 19
    • 17
    • 16
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of AR (aa689-919) expressed in E. Coli.
    克隆位点
    1A9D12
    亚型
    IgG1
    Top Product
    Discover our top product AR Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Zong, Chi, Wang, Yang, Zhang, Chen, Jiang, Li, Hong, Wang, Yun, Gu: "Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor." in: Molecular and cellular biology, Vol. 27, Issue 20, pp. 7125-42, (2007) (PubMed).

    Lindström, Wiklund, Adami, Bälter, Adolfsson, Grönberg: "Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development." in: Cancer research, Vol. 66, Issue 22, pp. 11077-83, (2006) (PubMed).

  • 抗原
    Androgen Receptor (AR)
    别名
    AR (AR 产品)
    别名
    AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody
    背景
    AR: androgen receptor. The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
    Synonyms: KD, AIS, TFM, DHTR, SBMA
    基因ID
    367
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
You are here:
客服