Angiopoietin 1 抗体 (ANGPT1) (Middle Region)

Details for Product anti-ANGPT1 Antibody No. ABIN965551, 供应商: Log in to see
抗原
  • AGP1
  • AGPT
  • ANG1
  • 1110046O21Rik
  • Ang-1
  • Ang1
  • Agpt
  • Agpt1
  • ang1
  • wu:fc76g06
  • ANG-1
  • angpt1
  • MGC80788
  • angiopoietin 1
  • angiopoietin 1 S homeolog
  • ANGPT1
  • Angpt1
  • angpt1
  • angpt1.S
抗原表位
Middle Region
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适用

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宿主

162
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1
克隆类型
多克隆
标记
This Angiopoietin 1 antibody is un-conjugated
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应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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选项
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免疫原 A synthetic peptide corresponding to a sequence in the middle region of human ANG1 , different from the related mouse sequence by two amino acids, and different from the related rat sequence by only one amino acid.< br/>Immunogen was affinity purified.
亚型 IgG
交叉反应 小鼠, 大鼠
交叉反应 (详细) No cross reactivity with other proteins.
产品特性 Rabbit IgG polyclonal antibody for Angiopoietin-1 (ANGPT1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
别名 Angiopoietin-1(ANG-1) (ANGPT1 Antibody 摘要)
背景 Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22. 3-q23 and 8p23.
途径 RTK signaling, Glycosaminoglycan Metabolic Process
限制 仅限研究用
状态 Lyophilized
溶解方式 Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
缓冲液 Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
储存液 Sodium azide, Thimerosal (Merthiolate)
注意事项 Avoid repeated freezing and thawing.
储存条件 -20 °C
储存方法 At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
有引用在: Compston: "Selective oestrogen receptor modulators: potential therapeutic applications." in: Clinical endocrinology, Vol. 48, Issue 4, pp. 389-91, 1998 (PubMed).

Cheung, Stewart, Marsden: "Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23." in: Genomics, Vol. 48, Issue 3, pp. 389-91, 1998 (PubMed).

背景 Suri, Jones, Patan, Bartunkova, Maisonpierre, Davis, Sato, Yancopoulos: "Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis." in: Cell, Vol. 87, Issue 7, pp. 1171-80, 1997 (PubMed).

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