Angiopoietin 1 抗体 (Middle Region)
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Quick Overview for Angiopoietin 1 抗体 (Middle Region) (ABIN965551)
抗原
See all Angiopoietin 1 (ANGPT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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交叉反应
- 小鼠, 大鼠
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交叉反应 (详细)
- No cross reactivity with other proteins.
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产品特性
- Rabbit IgG polyclonal antibody for Angiopoietin-1 (ANGPT1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human ANG1 , different from the related mouse sequence by two amino acids, and different from the related rat sequence by only one amino acid.< br/>Immunogen was affinity purified.
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
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: "Selective oestrogen receptor modulators: potential therapeutic applications." in: Clinical endocrinology, Vol. 48, Issue 4, pp. 389-91, (1998) (PubMed).
: "Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23." in: Genomics, Vol. 48, Issue 3, pp. 389-91, (1998) (PubMed).
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: "Selective oestrogen receptor modulators: potential therapeutic applications." in: Clinical endocrinology, Vol. 48, Issue 4, pp. 389-91, (1998) (PubMed).
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- Angiopoietin 1 (ANGPT1)
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别名
- Angiopoietin-1(ANG-1)
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背景
- Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22. 3-q23 and 8p23.
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process
抗原
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