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PRDM1 抗体 (C-Term)

This anti-PRDM1 antibody is a 兔 多克隆 antibody detecting PRDM1 in WB, ELISA, IHC 和 IP. Suitable for 人.
Rockland
产品编号 ABIN964913
Supplier Product No.: 600-401-b52
发货至: 中国

Quick Overview for PRDM1 抗体 (C-Term) (ABIN964913)

抗原

See all PRDM1 抗体
PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRDM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
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    C-Term

    Supplier Product No.

    600-401-b52

    Supplier

    Rockland

    原理

    PRDM1 BLIMP1 Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against human BLIMP1 protein.

    产品特性

    Synonyms: rabbit anti-Blimp-1 antibody, rabbit anti-PRDM-1 antibody, anti-PRDM1/BLIMP1 antibody, PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Beta-lymphocyte-induced maturation protein 1, positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, BLIMP1, BLIMP 1, PRDM1

    纯化方法

    The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.

    过滤

    Sterile filtered

    免疫原

    Immunogen: Anti-Blimp1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminus of human, mouse, and rat PRDM1/BLIMP1.

    Immunogen Type: Conjugated Peptide

    亚型

    IgG
  • 应用备注

    Immunohistochemistry Dilution: 5 μg/mL

    Application Note: This affinity purified antibody has been tested for use in ELISA, Immunohistochemistry, and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~88 kDa in size corresponding to BLIMP1 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:1,000

    Immunoprecipitation Dilution: 5-10 μg/mL

    ELISA Dilution: 1:20,000 - 1:40,000

    Other: User Optimized

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.15 mg/mL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store Blimp1 antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

    别名

    PRDM1

    背景

    Background: Anti-Blimp1 is ideal for Immunology, Epigenetic and Nuclear Signaling research. PRDM1/Blimp1 (PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-binding factor 1, or PRDI-BF1, or Beta-lymphocyte-induced maturation protein 1) is one of several transcription factors which drives the maturation of B-lymphocytes into Ig secreting cells. In the nucleus, PRDM1/BLIMP1 functions as a transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Transcription of the PRDM1 gene is increased upon virus induction. PRDM1/Blimp1 also interacts with PRMT5. Two alternatively spliced transcript variants that encode different isoforms have been reported.

    基因ID

    639, 25008939

    UniProt

    Q60636

    途径

    Regulation of Muscle Cell Differentiation
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