PRDM1 抗体 (Middle Region)
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北京 101111
Quick Overview for PRDM1 抗体 (Middle Region) (ABIN2792524)
抗原
See all PRDM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PRDM1 Antibody - middle region
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序列
- VEDDISVISV VEKEILAVVR KEKEETGLKV SLQRNMGNGL LSSGCSLYES
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交叉反应
- 牛, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 84%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against PRDM1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRDM1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection. ..." in: Cancer cell, Vol. 28, Issue 2, pp. 210-24, (2015) (PubMed).
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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别名
- PRDM1
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背景
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Background Information: PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Gene Name: PR domain containing 1, with ZNF domain
Alternative Symbols: BLIMP1, PRDI-BF1
Protein Name: PR domain zinc finger protein 1
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分子量
- 92 kDa
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基因ID
- 639
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NCBI登录号
- NP_878911
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UniProt
- Q86WM7
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途径
- Regulation of Muscle Cell Differentiation
抗原
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