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Interleukin 17a 抗体

Rockland 210-501-b32s IL17A 适用: 小鼠 ELISA, WB, FACS, MA 宿主: 大鼠 Monoclonal 20B4-G10-F5 unconjugated
Rockland
产品编号 ABIN964796
Supplier Product No.: 210-501-b32s
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
    • 81
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    小鼠
    宿主
    • 63
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    大鼠
    克隆类型
    • 68
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    单克隆
    标记
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    This Interleukin 17a antibody is un-conjugated
    应用范围
    • 71
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    ELISA, Western Blotting (WB), Flow Cytometry (FACS), Multiplex Assay (MA)
    Supplier Product No.
    210-501-b32s
    Supplier
    Rockland
    原理
    Mouse IL-17A Antibody
    交叉反应 (详细)
    This antibody is specific for mouse IL-17A protein.
    产品特性
    Synonyms: rat anti-IL-17A antibody, rat anti-interleukin17A antibody, Interleukin-17A cytokine, IL-17A, IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8
    纯化方法
    This monoclonal antibody is purified by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This Mouse IL-17A monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development.

    Immunogen Type: Recombinant Protein

    克隆位点
    20B4-G10-F5
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注

    Flow Cytometry Dilution: 1:500

    Application Note: IL-17 A antibody has been tested for use in western blotting, Flow Cytometry and ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 23 kDa in size corresponding to the mature mouse IL-17A protein, a non-glycosylated polypeptide chain consisting of 207 amino acids, by western blotting in appropriate cell lysate or extract.

    Western Blot Dilution: 1:1000

    ELISA Dilution: 1:10,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.94 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store IL-17A antibody at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL17a (IL17A 产品)
    背景
    Background: Mouse Interleukin-17A (IL-17A), also known as CTLA-8, is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Mouse IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58 % identity between the amino acid sequence of human and mouse IL-17A. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
    基因ID
    16171
    NCBI登录号
    NP_034682
    UniProt
    Q62386
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