IL-13 抗体
Quick Overview for IL-13 抗体 (ABIN964711)
抗原
See all IL-13 (IL13) 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-b55
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Supplier
- Rockland
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原理
- IL13 Antibody
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交叉反应 （详细）
- This antibody is specific for swine IL-13 protein.
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产品特性
- Synonyms: rabbit anti-Interleukin-13 antibody, rabbit anti-IL-13 antibody, IL13, Interleukin13, IL 13, Interleukin 13
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纯化方法
- This product was Protein-A purified from monospecific antiserum by chromatography.
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免疫原
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Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant protein raised in yeast, corresponding to mature swine IL-13 protein.
Immunogen Type: Recombinant Protein
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亚型
- IgG
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anti-Interleukin 13 (IL13) (AA 45-56) antibody
IL13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-146) antibodyIL13 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-146) antibodyIL13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Interleukin 13 (IL13) (AA 118-146) antibodyIL13 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-131) antibodyIL13 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 30-125) antibodyIL13 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 大鼠 ELISA, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal A130D 12G5 1E4 unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IHC, Neut, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: IL-13 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 13.2 kDa in size corresponding to swine IL-13 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1.5 to 2 μg/mL
ELISA Dilution: 1:11,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- IL13
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背景
- Background: Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. Anti-IL-13 antibody is ideal for investigators involved in Cancer and Immunology research.
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基因ID
- 396721, 189176151
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UniProt
- B3GDZ5
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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