TLR4 抗体 (PE)
Quick Overview for TLR4 抗体 (PE) (ABIN959964)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This has been demonstrated to block activation of monocytes with LPS.
-
纯化方法
- Protein G purified
-
免疫原
-
This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).
Type of Immunogen: Cells -
亚型
- IgG2a kappa
-
-
-
-
应用备注
-
Approved: Flo (1 - 2 μg/10 x106)
Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- PBS, 0.05 % BSA, 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Do not freeze! Sensitive to light.
-
储存条件
- 4 °C
-
储存方法
- Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Protect from light.
-
-
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
别名
- TLR4
-
背景
-
Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll -
基因ID
- 7099
-
UniProt
- O00206
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
-