TLR4 抗体 (PE)
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- 抗原 See all TLR4 抗体
- TLR4 (Toll-Like Receptor 4 (TLR4))
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适用
- 人, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR4 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This has been demonstrated to block activation of monocytes with LPS.
- 纯化方法
- Protein G purified
- 免疫原
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This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).
Type of Immunogen: Cells - 克隆位点
- HTA125
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TLR4 Primary Antibody
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- 应用备注
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Approved: Flo (1 - 2 μg/10 x106)
Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.05 % BSA, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze! Sensitive to light.
- 储存条件
- 4 °C
- 储存方法
- Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Protect from light.
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- 抗原
- TLR4 (Toll-Like Receptor 4 (TLR4))
- 别名
- TLR4 (TLR4 产品)
- 背景
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Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll - 基因ID
- 7099
- UniProt
- O00206
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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