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WWOX 抗体 (C-Term)

This anti-WWOX antibody is a 兔 多克隆 antibody detecting WWOX in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN955590
发货至: 中国

Quick Overview for WWOX 抗体 (C-Term) (ABIN955590)

抗原

See all WWOX 抗体
WWOX (WW Domain Containing Oxidoreductase (WWOX))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This WWOX antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 12
    • 9
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    AA 368-396, C-Term

    特异性

    This antibody detects WWOX / FOR (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 368-396 amino acids from the C-terminal region of human WWOX

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    WWOX (WW Domain Containing Oxidoreductase (WWOX))

    别名

    WWOX / FOR

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.Synonyms: FOR I, FOR II, FOR III, FOR IV, FOR1, FOR2, FOR3, Fragile site FRA16D oxidoreductase, WOX1, WOX2, WOX3, WW domain-containing oxidoreductase, WWOXdelta5-8, WWOXdelta6-8, WWOXv1, WWOXv2, WWOXv3, WWOXv4, WWOXv8

    基因ID

    51741

    NCBI登录号

    NP_057457
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