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TYROBP 抗体 (C-Term)

This anti-TYROBP antibody is a 兔 多克隆 antibody detecting TYROBP in WB, FACS, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN955408
发货至: 中国

Quick Overview for TYROBP 抗体 (C-Term) (ABIN955408)

抗原

See all TYROBP 抗体
TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TYROBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 84-113, C-Term

    特异性

    This antibody detects TYROBP / DAP12 (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 84~113 amino acids from the C-terminal region of human TYROBP

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

    别名

    TYROBP / DAP12

    背景

    TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.Synonyms: DNAX-activation protein 12, KARAP, Killer-activating receptor-associated protein, TYRO protein tyrosine kinase-binding protein

    基因ID

    7305

    NCBI登录号

    NP_003323
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