Transferrin 抗体
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Quick Overview for Transferrin 抗体 (ABIN955314)
抗原
See all Transferrin (TF) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is directed against Rat Transferrin.
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纯化方法
- This IgG fraction was isolated from a high titer antiserum by salt fractionation and DEAE ion exchange chromatography. It was titered against its immunogens, sterile filtered, and analyzed for immunoglobulin purity and protein concentration.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 7.8 mg IgG/ml
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- Transferrin (TF)
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背景
- Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin
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基因ID
- 24825
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NCBI登录号
- NP_001013128
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途径
- Transition Metal Ion Homeostasis
抗原
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