TOP3B 抗体 (C-Term)
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Quick Overview for TOP3B 抗体 (C-Term) (ABIN955293)
抗原
See all TOP3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 825-854, C-Term
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特异性
- This antibody detects TOP3B (C-term).
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 825-854 amino acids from the C-terminal region of human TOP3B
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
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别名
- TOP3B
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背景
- This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity, however, not all variants have been fully described.Synonyms: DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B1
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基因ID
- 8940
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NCBI登录号
- NP_003926
抗原
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