NKX2-1 抗体 (N-Term)
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北京 101111
Quick Overview for NKX2-1 抗体 (N-Term) (ABIN955203)
抗原
See all NKX2-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30, N-Term
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特异性
- This antibody recognizes human TTF1 / NKX2A at N-term.
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纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human NKX2-1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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别名
- TTF1 / NKX2A
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背景
- The NKX2-1 gene encodes a protein initially identified as a thyroid-specific transcription factor (TTF). TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NKX2-1, Nkx-2.1, TITF1, TTF-1, Thyroid nuclear factor 1, Thyroid transcription factor 1
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分子量
- 38596 Da
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基因ID
- 7080
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NCBI登录号
- NP_001073136
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
抗原
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