Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS with 0.09 % (W/V) Sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
NKX2-1
(NK2 Homeobox 1 (NKX2-1))
别名
TTF1 / NKX2A
背景
The NKX2-1 gene encodes a protein initially identified as a thyroid-specific transcription factor (TTF). TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NKX2-1, Nkx-2.1, TITF1, TTF-1, Thyroid nuclear factor 1, Thyroid transcription factor 1