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Recombinant NKX2-1 抗体

NKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 兔 Monoclonal NX2-1-1855R unconjugated Recombinant Antibody
产品编号 ABIN6940746
发货至: 中国
  • 抗原 See all NKX2-1 抗体
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    抗体类型
    Recombinant Antibody
    适用
    • 81
    • 36
    • 36
    • 1
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 29
    克隆类型
    • 42
    • 40
    单克隆
    标记
    • 41
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    This NKX2-1 antibody is un-conjugated
    应用范围
    • 45
    • 37
    • 30
    • 27
    • 20
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human full-length TTF-1 protein
    克隆位点
    NX2-1-1855R
    亚型
    IgG
    Top Product
    Discover our top product NKX2-1 Primary Antibody
  • 应用备注

    Positive Control: MAD109, MLE-15, H441-4 or H345 cells. Normal thyroid or lung.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    别名
    NKX2-1 (NKX2-1 产品)
    别名
    BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
    分子量
    40kDa
    基因ID
    7080
    UniProt
    P43699
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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