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SP1 抗体 (C-Term)

This anti-SP1 antibody is a 兔 多克隆 antibody detecting SP1 in WB, IF, IHC (p), FACS 和 EIA. Suitable for 人.
产品编号 ABIN954894
发货至: 中国

Quick Overview for SP1 抗体 (C-Term) (ABIN954894)

抗原

See all SP1 抗体
SP1 (Sp1 Transcription Factor (SP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
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    AA 684-715, C-Term

    特异性

    This antibody recognizes SP1 / TSFP1 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Purified through a Protein A column followed by peptide affinity purification

    免疫原

    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 684-715aa) of human SP1 / TSFP1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SP1 (Sp1 Transcription Factor (SP1))

    背景

    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.Synonyms: Transcription factor Sp1

    基因ID

    6667

    NCBI登录号

    NP_003100

    途径

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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