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RAD17 抗体 (Middle Region)

RAD17 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN954430
发货至: 中国
  • 抗原 See all RAD17 抗体
    RAD17
    抗原表位
    • 20
    • 15
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 225-254, Middle Region
    适用
    • 98
    • 30
    • 19
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 92
    • 5
    • 3
    • 1
    克隆类型
    • 97
    • 3
    多克隆
    标记
    • 49
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This RAD17 antibody is un-conjugated
    应用范围
    • 52
    • 31
    • 26
    • 26
    • 12
    • 11
    • 10
    • 10
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human RAD17 (Center).
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 225-254 amino acids from the Central region of Human RAD17
    亚型
    Ig Fraction
    Top Product
    Discover our top product RAD17 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RAD17
    别名
    RAD17 (RAD17 产品)
    背景
    The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.Synonyms: Cell cycle checkpoint protein RAD17, R24L, RF-C/activator 1 homolog
    分子量
    77055 Da
    基因ID
    5884
    NCBI登录号
    NP_002864
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