RAD17 抗体 (Middle Region)
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北京 101111
Quick Overview for RAD17 抗体 (Middle Region) (ABIN954430)
抗原
See all RAD17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-254, Middle Region
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特异性
- This antibody recognizes Human RAD17 (Center).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 225-254 amino acids from the Central region of Human RAD17
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亚型
- Ig Fraction
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anti-RAD17 (RAD17) (AA 1-584) antibody
RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 391-670) antibodyRAD17 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 1-110) antibodyRAD17 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-RAD17 (RAD17) (AA 1-270) antibodyRAD17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) antibodyKD Validated RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 621-670) antibodyRAD17 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) antibodyRAD17 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 3-10E-010 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RAD17
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别名
- RAD17
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背景
- The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.Synonyms: Cell cycle checkpoint protein RAD17, R24L, RF-C/activator 1 homolog
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分子量
- 77055 Da
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基因ID
- 5884
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NCBI登录号
- NP_002864
抗原
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