Prothrombin 抗体
Quick Overview for Prothrombin 抗体 (ABIN954323)
抗原
See all Prothrombin (F2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific for Human Prothrombin (CaPro-20).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Protein G Chromatography of Ascitic fluid.
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免疫原
- Human Prothrombin (CaPro-20) purified from plasma.
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亚型
- IgG1
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anti-Coagulation Factor II (thrombin) (F2) (AA 263-362) antibody
F2 适用: 人 WB, IP, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 324-617) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 44-200) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (Middle Region) antibodyF2 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) antibodyF2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E1 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 44-200) antibodyF2 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (Internal Region) antibodyF2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 1-622) antibodyF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (N-Term) antibodyF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 67-124) antibodyF2 适用: 人 WB, IHC, ICC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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别名
- Prothrombin (F2)
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背景
- Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia. Prothrombin is a 72 kDa blood clotting glycoprotein formed by and stored in the Liver. Prothrombin is present in the blood plasma and is converted to the key blood clotting agent thrombin, when blood vessels are damaged. Factor VII, another important haemostasis protein can be converted to VIIa by Factor IXa or Thrombin.Synonyms: Coagulation factor II
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基因ID
- 2147
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NCBI登录号
- NP_000497
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UniProt
- P00734
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途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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