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PNN 抗体 (Middle Region)

This anti-PNN antibody is a 兔 多克隆 antibody detecting PNN in WB, IF, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN954147
发货至: 中国

Quick Overview for PNN 抗体 (Middle Region) (ABIN954147)

抗原

See all PNN 抗体
PNN (Pinin, Desmosome Associated Protein (PNN))

适用

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宿主

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克隆类型

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多克隆

标记

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This PNN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 216-248, Middle Region

    特异性

    This antibody recognizes Human Pinin / PNN (Center).

    纯化方法

    Affinitty Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 216-248 amino acids from the Central region of human PNN.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PNN (Pinin, Desmosome Associated Protein (PNN))

    别名

    Pinin / PNN

    背景

    Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.Synonyms: 140 kDa nuclear and cell adhesion-related phosphoprotein, DRS, DRSP, Desmosome-associated protein, Domain-rich serine protein, MEMA, Nuclear protein SDK3

    分子量

    81614 Da

    基因ID

    5411

    NCBI登录号

    NP_002678
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