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PNN 抗体 (Internal Region)

PNN 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257423
发货至: 中国
  • 抗原 See all PNN 抗体
    PNN (Pinin, Desmosome Associated Protein (PNN))
    抗原表位
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 45
    • 22
    • 10
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 4
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNN antibody is un-conjugated
    应用范围
    • 36
    • 24
    • 16
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PNN Antibody detects endogenous levels of total PNN.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PNN, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PNN Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PNN (Pinin, Desmosome Associated Protein (PNN))
    别名
    PNN (PNN 产品)
    别名
    DRS antibody, DRSP antibody, SDK3 antibody, memA antibody, wu:fb24d03 antibody, pnn antibody, MGC88923 antibody, PNN antibody, AU045199 antibody, D12Ertd512e antibody, CG8383 antibody, Dmel\\CG8383 antibody, dPnn antibody, pinin, desmosome associated protein antibody, pinin antibody, Pinin antibody, PNN antibody, Pnn antibody, pnn antibody, LOC100380709 antibody
    背景

    Description: Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.

    Gene: PNN

    分子量
    85 kDa
    基因ID
    5411
    UniProt
    Q9H307
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