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PDE4B 抗体 (Middle Region)

This anti-PDE4B antibody is a 兔 多克隆 antibody detecting PDE4B in WB, FACS 和 EIA. Suitable for 人.
产品编号 ABIN954065
发货至: 中国

Quick Overview for PDE4B 抗体 (Middle Region) (ABIN954065)

抗原

See all PDE4B 抗体
PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

适用

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宿主

  • 33
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克隆类型

  • 32
  • 18
多克隆

标记

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This PDE4B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
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    AA 196-225, Middle Region

    特异性

    This antibody recognizes Human PDE4B (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 196-225 amino acids from the Central region of Human PDE4B

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

    别名

    PDE4B

    背景

    This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: 5'-cyclic phosphodiesterase 4B, DPDE4, EC=3.1.4.17, PDE32, PDE4B, cAMP-specific 3'

    分子量

    83343 Da

    基因ID

    5142

    NCBI登录号

    NP_001032416

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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