Neurofibromin 1 抗体 (Internal Region)
Quick Overview for Neurofibromin 1 抗体 (Internal Region) (ABIN953662)
抗原
See all Neurofibromin 1 (NF1) 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- Internal Region
- 
                                            特异性
- This antibody detects endogenous levels of total NF1 protein.
- 
                                            交叉反应 (详细)
- 
                        Species reactivity (expected):Mouse and Rat.
 Species reactivity (tested):Human.
- 
                                            纯化方法
- Immunoaffinity Chromatography
- 
                                            免疫原
- Synthetic peptide from Human NF1. Epitope: Internal.
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- Optimal working dilution should be determined by the investigator.
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            浓度
- 1.0 mg/mL
- 
                                            缓冲液
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            注意事项
- Avoid repeated freezing and thawing.
- 
                                            储存条件
- 4 °C/-20 °C
- 
                                            储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
 
- 
                                            
- 
    - Neurofibromin 1 (NF1)
- 
                                            别名
- Neurofibromin
- 
                                            背景
- Mutations linked to neurofibromatosis type 1 led to the identification of NF1. NF1 encodes the protein neurofibromin, which appears to be a negative regulator of the ras signal transduction pathway. In addition to type 1 neurofibromatosis, mutations in NF1 can also lead to juvenile myelomonocytic leukemia. Alternatively spliced NF1 mRNA transcripts have been isolated, although their functions, if any, remain unclear.Synonyms: NF-1, NF1
- 
                                            基因ID
- 4763
- 
                                            NCBI登录号
- NP_000258
- 
                                            途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
 抗原
- 
                    
 
                                     
                                     
                                    