Neurofibromin 1 抗体 (AA 1551-1600)
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Quick Overview for Neurofibromin 1 抗体 (AA 1551-1600) (ABIN1534476)
抗原
See all Neurofibromin 1 (NF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1551-1600
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原理
- Neurofibromin Antibody
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特异性
- Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Neurofibromin 1 (NF1)
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别名
- NF1
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背景
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Synonyms: NF1; Neurofibromin; Neurofibromatosis-related protein NF-1
Background: This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: NF1
Protein Name: Neurofibromin
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分子量
- 319 kDa
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基因ID
- 4763
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OMIM
- 114500
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UniProt
- P21359
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途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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