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WHSC2 抗体 (Middle Region)

The 兔 多克隆 anti-WHSC2 antibody is suitable to detect WHSC2 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN953645
发货至: 中国
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Quick Overview for WHSC2 抗体 (Middle Region) (ABIN953645)

抗原

See all WHSC2 抗体
WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

适用

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宿主

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克隆类型

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多克隆

标记

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This WHSC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
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    AA 261-290, Middle Region

    特异性

    This antibody detects NELF-A (Center).

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 261-290 amino acids from the Central region of human WHSC2

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

    别名

    NELF-A

    背景

    This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.Synonyms: NELFA, Negative elongation factor A, P/OKcl.15, WHSC2

    基因ID

    7469

    NCBI登录号

    NP_005654

    途径

    Chromatin Binding
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