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MLH1 抗体 (Middle Region)
MLH1
适用: 人
WB, FACS, EIA
宿主: 兔
Polyclonal
unconjugated
MLH1抗体详情
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抗原
See all MLH1 抗体
MLH1
(MutL Homolog 1 (MLH1))
抗原表位
All epitopes for MLH1 抗体
AA 459-488, Middle Region
适用
All reactivities for MLH1 抗体
人
宿主
All hosts for MLH1 抗体
兔
克隆类型
All clonalities for MLH1 抗体
多克隆
标记
All conjugates for MLH1 抗体
This MLH1 antibody is un-conjugated
应用范围
All applications for MLH1 抗体
Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
特异性
This antibody recognizes MLH1.
交叉反应 (详细)
Species reactivity (tested):Human
纯化方法
Purified through a Protein A column followed by peptide affinity purification
免疫原
Synthetic peptide - KLH conjugated - corresponding to the central region (between 459-488aa) of human MLH1.
亚型
Ig Fraction
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Discover our top product MLH1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS with 0.09 % (W/V) Sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
MLH1目标详情
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抗原
MLH1
(MutL Homolog 1 (MLH1))
别名
MLH1 (MLH1 产品 )
别名
CG11482 antibody, Dmel\\CG11482 antibody, dmlh-1 antibody, dmlh1 antibody, zgc:66301 antibody, MLH1 antibody, LOC100232198 antibody, 1110035C23Rik antibody, AI317206 antibody, AI325952 antibody, AI561766 antibody, COCA2 antibody, FCC2 antibody, HNPCC antibody, HNPCC2 antibody, hMLH1 antibody, mutL homolog 1 antibody, CG11482 gene product from transcript CG11482-RB antibody, mutL homolog 1 S homeolog antibody, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody, DNA mismatch repair protein Mlh1 antibody, MLH1 antibody, Mlh1 antibody, mlh1.S antibody, mlh1 antibody, LOC588545 antibody
背景
The MLH1 gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.Synonyms: COCA2, DNA mismatch repair protein Mlh1
基因ID
4292
NCBI登录号
NP_000240
途径
DNA Damage Repair , Production of Molecular Mediator of Immune Response
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