MLH1 抗体 (Middle Region)
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Quick Overview for MLH1 抗体 (Middle Region) (ABIN953460)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 459-488, Middle Region
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特异性
- This antibody recognizes MLH1.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 459-488aa) of human MLH1.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
- The MLH1 gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.Synonyms: COCA2, DNA mismatch repair protein Mlh1
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基因ID
- 4292
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NCBI登录号
- NP_000240
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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