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MECP2 抗体 (N-Term)

MECP2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN953366
发货至: 中国
  • 抗原 See all MECP2 抗体
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    抗原表位
    • 18
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 103
    • 41
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
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    宿主
    • 102
    • 8
    • 1
    克隆类型
    • 103
    • 8
    多克隆
    标记
    • 65
    • 10
    • 8
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MECP2 antibody is un-conjugated
    应用范围
    • 82
    • 66
    • 36
    • 30
    • 12
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human MeCP2 (N-term).
    纯化方法
    Protein A column, followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide selected from the N-terminal region of Human MeCP2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MECP2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    别名
    MeCP2 (MECP2 产品)
    别名
    AUTSX3 antibody, MRX16 antibody, MRX79 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, 1500041B07Rik antibody, BB130002 antibody, D630021H01Rik antibody, Mbd5 antibody, WBP10 antibody, wu:fk96a04 antibody, zgc:111857 antibody, methyl-CpG binding protein 2 antibody, methyl CpG binding protein 2 antibody, methyl-CpG binding protein 2 S homeolog antibody, MECP2 antibody, Mecp2 antibody, mecp2 antibody, mecp2.S antibody
    背景
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.Synonyms: MeCP-2 protein, Methyl-CpG-binding protein 2
    分子量
    52441 Da
    基因ID
    4204
    NCBI登录号
    NP_001104262
    途径
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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