MECOM 抗体 (Middle Region)
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北京 101111
Quick Overview for MECOM 抗体 (Middle Region) (ABIN953364)
抗原
See all MECOM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-109, Middle Region
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特异性
- This antibody recognizes Human and Mouse MDS1 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 80-109 amino acids from the Central region of human MDS1 Genename: MECOM
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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别名
- MDS1
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背景
- MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
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分子量
- 18696 Da
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基因ID
- 2122
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NCBI登录号
- NP_004982
抗原
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