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MECOM 抗体 (Middle Region)

This anti-MECOM antibody is a 兔 多克隆 antibody detecting MECOM in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN953364
发货至: 中国

Quick Overview for MECOM 抗体 (Middle Region) (ABIN953364)

抗原

See all MECOM 抗体
MECOM (MDS1 and EVI1 Complex Locus (MECOM))

适用

  • 57
  • 18
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 45
  • 14
  • 1

克隆类型

  • 48
  • 12
多克隆

标记

  • 35
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MECOM antibody is un-conjugated

应用范围

  • 44
  • 34
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 12
    • 9
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-109, Middle Region

    特异性

    This antibody recognizes Human and Mouse MDS1 (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 80-109 amino acids from the Central region of human MDS1 Genename: MECOM

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MECOM (MDS1 and EVI1 Complex Locus (MECOM))

    别名

    MDS1

    背景

    MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1

    分子量

    18696 Da

    基因ID

    2122

    NCBI登录号

    NP_004982
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