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MAP4K1 抗体

MAP4K1 适用: 人 WB, IHC (p), IP 宿主: 小鼠 Monoclonal 2A1 unconjugated
产品编号 ABIN953299
发货至: 中国
  • 抗原 See all MAP4K1 抗体
    MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
    适用
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    宿主
    • 52
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    小鼠
    克隆类型
    • 54
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    单克隆
    标记
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    This MAP4K1 antibody is un-conjugated
    应用范围
    • 45
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    Recognizes MAP4K1
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulfate Precipitation
    免疫原
    Recombinant Human protein purified from E. coli (His/ABD-HPK1).
    克隆位点
    2A1
    亚型
    IgG1
    Top Product
    Discover our top product MAP4K1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % Sdium Azide and 50 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
    别名
    MAP4K1 (MAP4K1 产品)
    别名
    HPK1 antibody, Hpk1 antibody, mHPK1 antibody, mitogen activated protein kinase kinase kinase kinase 1 antibody, mitogen-activated protein kinase kinase kinase kinase 1 antibody, Map4k1 antibody, MAP4K1 antibody
    背景
    HPK1, a KHS protein kinase, is an upstream activator of the stress-activated protein kinase (SAPK) signaling pathway. The protein has a structure similar to other GCK (Group I) kinases and contains four consensus SH3 binding motifs, which have been shown to interact with the SH3 motifs of the MAP kinase kinase kinases MLK3 and MEKK1 and several adapter proteins that couple to tyrosine kinases, including BASH, Blnk, Clnk, Crk, CrkL and Grb2. Additionally, HPK1 has been shown to be phosphorylated and activated by the tyrosine kinase c-Abl in response to genotoxic agents. At least two mRNA transcripts have been reported.Synonyms: HPK1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEKKK 1, Mitogen-activated protein kinase kinase kinase kinase 1
    基因ID
    11184
    NCBI登录号
    NP_001036065
    UniProt
    Q92918
    途径
    TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
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