MXD3 抗体 (N-Term)
Quick Overview for MXD3 抗体 (N-Term) (ABIN953278)
抗原
See all MXD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-56, N-Term
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特异性
- This antibody recognizes human MAD3 at N-term.
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纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 27-56aa) of human MAD3
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MXD3 (MAX Dimerization Protein 3 (MXD3))
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别名
- MAD3
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背景
- The MXD3 gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The Max-associated protein 3 / MAD3 forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.Synonyms: MAD-3, MXD3, Max-interacting transcriptional repressor MAD3
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分子量
- 23477 Da
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基因ID
- 83463
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NCBI登录号
- NP_001136407
抗原
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