KREMEN2 抗体 (Middle Region)
Quick Overview for KREMEN2 抗体 (Middle Region) (ABIN953114)
抗原
See all KREMEN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 247-276, Middle Region
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特异性
- This antibody reacts to KREMEN2.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2
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亚型
- Ig Fraction
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anti-Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 121-220) antibody
KREMEN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 1-420) antibodyKREMEN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 200-360) antibodyKREMEN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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别名
- Kremen Protein 2
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背景
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.Synonyms: Dickkopf receptor 2, KREMEN2, KRM2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose
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基因ID
- 79412
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NCBI登录号
- NP_078783
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途径
- WNT signaling
抗原
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