KDM4C 抗体 (C-Term)
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Quick Overview for KDM4C 抗体 (C-Term) (ABIN952976)
抗原
See all KDM4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1030-1056, C-Term
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特异性
- This antibody recognizes Human JMJD2C / KDM4C (C-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C Genename: KDM4C
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
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别名
- JMJD2C / KDM4C
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背景
- This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.Synonyms: GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KIAA0780, Lysine-specific demethylase 4C
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分子量
- 119982 Da
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基因ID
- 23081
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NCBI登录号
- NP_001140166
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途径
- Nuclear Hormone Receptor Binding, Warburg Effect
抗原
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